Sugar begins entering your bloodstream within minutes of eating and usually clears from your system within two to three hours ...

Recent advances in glucose management are reshaping our understanding of cognitive decline and dementia prevention. Energy ...

The mechanisms driving the cardiovascular and renal benefits of therapies targeting intestinal hormones in type 2 diabetes ...

In peripheral tissues, insulin promotes glucose uptake in adipose tissue and inhibits lipolysis, promoting fat storage in adipocytes (88, 89), and in the central nervous system, insulin acts as an ...

This research is the first to reveal that the microbial-derived bile acid Trp-CA improves glucose homeostasis by activating MRGPRE. It provides a new potential drug target and therapeutic strategy ...

It elucidated the novel mechanism by which Trp-CA activates MRGPRE, promoting GLP-1 secretion through dual pathways: Gs-cAMP signaling and β-arrestin-1-mediated ALDOA phosphorylation, thereby ...