Cryo-EM and protein NMR 3D snapshots reveal sophisticated mechanism of action of a bacterial Tc toxin Date: August 3, 2022 Source: Max Planck Institute of Molecular Physiology Summary: ...

Setting up the opponent by reducing the striking distance "For a long time, we struggled with obtaining a complete picture of the intoxication process, since we lacked the structural data of the ...

Xu, X., et al. (2020) Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a di-heptamer macromolecular assembly.Proceedings of the National Academy of ...

Hospital acquired infections are a serious public health concern. According to the Centers for Disease Control (CDC), the bacteria Clostridium difficile is estimated to have caused around half a ...

However, rather than concentrating on the secretory mechanism, a focus of several laboratories at other institutions, Connell and colleagues Jason Folster, a doctoral student, and Daniel Metzger, UB ...

Antibody-mediated protection mechanism expands tuberculosis treatment options May 30, 2025 Innovative immunotherapy shows promise against aggressive T cell cancers ...