Fungal infections have emerged as a major global health concern, further exacerbated by their frequent under/misdiagnosis or underreporting, leading to ...

(RTTNews) - CytoDyn Inc. (CYDY.OB), a biotechnology company, Tuesday announced new data suggesting a novel mechanism of action of leronlimab for the treatment of solid tumors. CytoDyn analyzed ...

With only a few exceptions, these drugs were discovered by screening in animal models which do not discriminate on the basis of mechanism of action. Over the last 35 years, over 34,000 ...

Amphista applies its proprietary Eclipsys™ platform to generate unique, bifunctional Targeted Glue® therapeutics with a differentiated mechanism and leading drug-like properties. Our portfolio offers ...

“Its mechanism of action is fairly unique in dermatology,” Bissonnette told Healio. “It is not a protein, it is a small peptide that can be given orally, and it blocks the interaction ...

Understanding a drug’s mechanism of action (MOA) can greatly increase the likelihood of successful clinical trials by identifying biomarkers of patient response and providing a rationale for ...

Gut microbiota as a biomarker for the efficacy of pembrolizumab in patients with advanced urothelial carcinoma treated in a prospective multicenter study. NECTIN4 RNA expression and clinical outcomes ...

Furthermore, the evidence consistently demonstrated that the onset of vancomycin-induced neutropenia occurred with prolonged use. The exact mechanism of vancomycin-induced neutropenia is unknown ...

A research team now describes a new mechanism of action that kills cancer cells through ferroptosis. In a first, a Bochum-based team has produced a substance capable of sending cancer cells into ...

There are still many enigmas about the mechanism of action of metformin, the most prescribed drug to treat diabetes mellitus, also known as type 2 diabetes. Now, a review article published in the ...

Sun Baolin from the University of Science and Technology of China (USTC) revealed the mechanism of transcriptional regulation via S-nitrosylation for vancomycin resistance in Staphylococcus aureus.

Bruno Bockorny, MD, explains the mechanism of action of botensilimab and its use in combination with balstilimab for ovarian cancer treatment. Bruno Bockorny, MD, assistant professor of medicine with ...