Newly discovered mechanism of T-cell control can interfere with cancer immunotherapies Date: May 3, 2024 Source: German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) Summary ...

The research team investigated the regulatory mechanisms that guide the optimal differentiation of T cells into specific lineages while inhibiting others.

A research team has discovered a previously unknown mechanism that could explain why many patients with aggressive B-cell lymphoma do not respond to CAR-T cell therapy in the long term. The ...

Integrated biomarker analyses confirm viral replication, interferon signaling, and a surge in tumor-infiltrating lymphocytes ...

Autoimmune diseases, such as multiple sclerosis (MS), inflammatory bowel disease (IBD), and rheumatoid arthritis (RA), affect ...

Li, G. (2025) Orientation of Drug Development: Focusing on Gene Expression Alterations, Giving up the Mechanisms of Action of Drugs. Open Access Library Journal, 12, 1-4. doi: 10.4236/oalib.1113717 .

Mesenchymal stem cell therapy lessens disability and brain lesions in MS patients, according to a review of published studies ...

Psilocybin, the psychoactive compound found in 'magic' mushrooms, may help delay aging by increasing the cellular lifespan of ...

U.S. and Chinese researchers appear to have unlocked a novel way to stop T cells from attacking the body in MS and other ...

Researchers found that bioengineered CAR-T cells when mixed with other immune cells can "donate" proteins, suggesting possible new avenues for therapies.

Orca-T shows significant promise in reducing chronic graft-vs-host disease and improving survival rates in allogeneic transplant patients with hematologic malignancies.

Activated T cells that carry a certain marker protein on their surface are controlled by natural killer (NK) cells, another cell type of the immune system. In this way, the body presumably curbs ...