A team of international researchers led by scientists at City of Hope have demonstrated a way to boost thymic function after ...

Collaboration to explore the immunoregulation of NK and T cells within the tumor microenvironment (TME) by CAPTN-3, with the goal of enhancing ...

A team of international researchers led by scientists at City of Hope, one of the largest and most advanced cancer research and treatment organization ...

Researchers found that bioengineered CAR-T cells when mixed with other immune cells can "donate" proteins, suggesting ...

There is potential for Tregs and amphiregulin to be used in patients receiving cancer therapies to ameliorate immune function.

HCW Biologics (HCWB) announced that it has received clearance of its Investigational New Drug Application, IND, from the U.S. Food and Drug ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA vaccines and double-stranded RNA (dsRNA) therapies. But while health care ...

However, activated NK cells can also kill MSCs. MSCs inhibit T-cell proliferation through ... This Review discusses the targets and mechanisms of MSC-mediated immunomodulation and the possible ...

31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T ... cells' in-house DNA repair ...

These studies indicate that Crohn's disease and ulcerative colitis are heterogeneous diseases characterized by various genetic abnormalities that lead to overly aggressive T-cell responses to a ...

In line with that, our review highlights the well-accepted mechanisms of action and resistance to the therapy and ... of downstream cascades to promote numerous effects, including cell growth, ...

A new advance may make it possible to use off-the-shelf CAR T cells provided by healthy donors. The new approach studied in mice equipped CAR T cells with the viral protein Nef.