The era of predictive modeling enhanced with machine learning and artificial intelligence (AI) to aid clinical ...

Patients with type 2 diabetes mellitus are at a higher risk of developing heart failure compared with the healthy population. In recent landmark clinical trials, sodium-glucose co-transporter 2 (SGLT2 ...

In this article, we will review the pharmacology and mechanisms of action of LCM, and evaluate its efficacy and safety as adjunctive therapy at daily doses of up to 400 mg in patients with ...

In this GEN webinar, Dave Lahr, PhD, Senior Director of Bioinformatics at Foghorn Therapeutics, discusses chromatin regulation and epigenetic mechanisms that shape transcriptional responses to ...

Hydrogels have been used in a multitude of biomedical applications for this reason. The purpose of this review is to explore some of the hydrogel systems that have been designed for this purpose, ...

Small-molecule inhibitors of FSP1 have been developed, but our understanding of their mechanism of action remains limited. Here, we solve the first crystal structure of FSP1 in complex with an FSP1 ...

(RTTNews) - CytoDyn Inc. (CYDY.OB), a biotechnology company, Tuesday announced new data suggesting a novel mechanism of action of leronlimab for the treatment of solid tumors.

Theralase(R) Has Discovered a New Mechanism of Action in Its War on Cancer; Specifically, Ruvidar’s(TM) Ability to Inhibit DeUbiquitinating Enzymes, an Important Class of Enzymes Which Have Been ...

Circle Pharma, a clinical-stage biopharmaceutical company focused on developing cell-permeable macrocycle therapeutics, today announced a late-breaking poste ...

CELEBRATION, Fla., April 17, 2025 (GLOBE NEWSWIRE) -- Zevra Therapeutics, Inc. (NasdaqGS: ZVRA) (Zevra, or the Company), a commercial-stage company focused on providing therapies for people living ...

Panelists discuss how amyloid-targeting therapies for Alzheimer disease represent a breakthrough drug class that works by binding to and removing beta-amyloid plaques through various mechanisms ...

This finding is consistent with 8-azaguanine’s known mechanism of action as an antimetabolite that resembles the purine base guanine (42) and reportedly the polyploid-specific disruptor of ...