The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the ...
All physicians are faced with the challenge of how to help patients with no approved therapies for their diseases. What are ...
In line with that, our review highlights the well-accepted mechanisms of action and resistance to the therapy and discusses the progress that has been made toward successfully overcoming this ...
Structural and cellular assays and molecular dynamics simulations reveal the mechanism of action of γ-glutamyl carboxylase, which involves cholesterol and vitamin K. Protein kinase R-like ...
Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China Key Laboratory of Mental Health of the Ministry of Education, Southern Medical ...
This article will review the mechanisms of activation of alternative, classical, and lectin pathways, the formation of C3 and C5 convertases, the action of anaphylatoxins, and the ...
Phys.org on MSN9d
Sleeping bacteria: New study uncovers mechanisms of dormancy involving protein aggregationResearchers at the VIB-KU Leuven Center for Microbiology and the VIB-KU Leuven Center for Brain & Disease Research have ...
Copy number variants (CNVs) arise by homologous recombination (HR) between repeated sequences (recurrent CNVs) or by non-homologous recombination mechanisms that occur throughout the genome (non ...
CardioOncology, shows that administration of the SGLT2 inhibitor empagliflozin to pigs receiving anthracyclines preserves ...
The discovery and development of GLP-1 receptor agonists for type 2 diabetes and obesity is a bench-to-bedside success story.1 Multiple GLP-1 receptor agonists are now in clinical use, such as ...
The research groups led by Associate Professor Masaki Sone from the Faculty of Science, Toho University, and Professor Hitoshi Okazawa from Institute of Science Tokyo and Maastricht University in the ...
Glucagon-like peptide 1 receptor agonists (GLP1RA)—medications for type 2 diabetes and obesity that have recently been making ...
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