The application of machine learning algorithms to predict the mechanism of action (MoA) of drugs can be highly valuable and enable the discovery of new uses for known molecules. The developed methods ...

Cite this: Lacosamide: Pharmacology, Mechanisms of Action and Pooled Efficacy and Safety Data in Partial-Onset Seizures - Medscape - Jan 01, 2009.

In part 2 (fed conditions trial), the mean AUC 0-12 ratio was 1.16 with a 90% CI of 0.92, 1.47, and the mean C max ratio was 1.21 with a 90% CI of 0.92, 1.59. The upper limit of the 90% CI was ...

However, this difference was not statistically significant and, because of the characteristics of the mechanism of action of omeprazole and the formulation type, this difference also cannot be ...

This study evaluated the growth-inhibiting properties of CIP against Babesia spp. and investigated the mechanism of CIP on B. gibsoni. The half inhibitory concentration (IC 50) values of CIP against ...

Metal–organic frameworks (MOFs) exhibit a diverse array of applications in the fields of adsorption, catalysis, sensing, and separation. However, the limited water stability of MOFs poses challenges ...

The mechanism of action (MoA) of a clickable fatty acid analogue 8-(2-cyclobuten-1-yl)octanoic acid (DA-CB) has been investigated for the first time. Proteomics, metabolomics, and lipidomics were ...