An investigational oral targeted therapy, zipalertinib (CLN-081), demonstrated meaningful tumor responses and a manageable ...

Merus N.V. Publishes Mechanism of Action for Petosemtamab Targeting EGFR and LGR5 in Cancer Journal "Cancers" May 15, 2025 — 08:14 am EDT Written by None for Quiver Quantitative -> ...

ALX Oncology’s second pipeline candidate, ALX2004, is a novel EGFR-targeted antibody-drug conjugate with a differentiated mechanism of action and is anticipated to enter Phase 1 trials mid-2025.

The FDA granted accelerated approval to atrasentan (Vanrafia) for the reduction of proteinuria in adults with primary immunoglobulin A (IgA) nephropathy, maker Novartis announced late on Wednesday ...

This brief but important review discusses mechanisms of action of antiseizure drugs, with a focus on the newly approved lacosamide, and it also describes why some anti-seizure drugs actually cause ...

Broadcast Date: Wednesday, March 26, 2025 Time: 8:00 am PT, 11:00 am ET, 16:00 CET ...

Objective: Non-small cell lung cancer (NSCLC), as the most common type of lung cancer, has a high rate of metastasis and mortality. A large number of studies have proved that traditional Chinese ...

However, in terms of the whole range of natural drugs, the mechanisms of anti-OC are more diverse, which is related to the complex and diverse structure of natural drugs (26). As expected, natural ...

LEO Pharma A/S, a global leader in medical dermatology, today announced positive results from the Phase 2a Mechanism of Action (MoA) trial, which assessed the mechanistic impact of investigational ...

So EGFR -mutant non–small cell lung cancer is quite common—20% to 25% in patients—and we're talking specifically about exon 19 del [deletion] and L858R.