All three cases were initially evaluated with broad immunohistochemical panels that did not include specific mast cell markers. Case 2 highlights the potential immunophenotypic pitfalls of this ...

Histidine decarboxylase is one of the enzymes of the amine precursor uptake and decarboxylation system and is known to be distributed in mast ... markers. On the other hand, large-cell carcinoma ...

The former also showed elevated markers of endothelial activation ... was not identified, it being a specific product of mature mast cells. These precursors may migrate into the lung since ...

Patients with CD2-negative mast cells have nearly 3 times higher odds of disease spread to the spleen, liver, and/or lymph nodes. While CD25 and CD30 are useful diagnostic markers for SM ...

In a recent study published in Neuron, researchers investigate the role of the mast-cell-specific receptor Mas-related G-protein-coupled receptor B2 (MrgprB2) in alcohol-withdrawal-induced ...

If we had a way to inactivate the mast cells that respond to specific allergens, then we could stop dangerous immune responses in severe situations like anaphylaxis as well as less serious ...

The study emphasizes that mastocytosis is not solely driven by mast cells ... that the identified proteins are specific to mastocytosis rather than a general marker of blood disorders.