Myc is a cancer-causing gene responsible for disrupting the normal 24-hour internal rhythm and metabolic pathways in cancer cells, found a team led by researchers from the Perelman School of ...

and synthetic lethality-wherein pathways essential to MYC-overexpressing cells are selectively disrupted. These methods aim to exploit the vulnerabilities of cancer cells that depend heavily on ...

UC researchers have found how the MYC oncogene fuels lymphoma by altering cell metabolism, paving the way for targeted ...

Researchers found that altering key enzymes involved in redox balance could disrupt the metabolism of Myc-driven lymphomas, ...

But eventually, the immune-attracting pathways are turned off ... some of the immune cells affected by excess MYC expression in prostate cancer - are already in development and are potential ...

In a new study published in the journal Cell Reports Medicine, a team of scientists at Baylor College of Medicine took a closer look at the molecular pathways metastatic cancer cells use ... factor ...

However, the molecular pathways and mechanisms underlying metastasis are not fully understood. Cancer is characterized ... and the transcription factor Myc. The Myc gene is a known proto-oncogene ...

a team of Moffitt Cancer Center researchers demonstrated a possible alternative approach. They showed that MYC activates a downstream pathway that chemically modifies a protein called eIF5A ...

Research from the University of Cincinnati reveals how the MYC oncogene alters PRPS enzymes, impacting redox homeostasis and ...

PHILADELPHIA - Myc is a cancer-causing gene responsible for disrupting the normal 24-hour internal rhythm and metabolic pathways in cancer cells, found a team led by researchers from the Perelman ...