This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...
Top panel: Overview of lysosomes and their interacting organelles within the endolysosomal system. Lysosomal fusion and fission with endosomes, autophagosomes, and phagosomes are critical for their ...
This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...
Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea Department of Biosystems and Bioengineering, KRIBB School of Biotechnology, ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. As a common and severe cerebrovascular disease ...
Lysosomes are dynamic organelles integral to cellular homeostasis, secretory pathways, immune responses, and cell death regulation. In cancers, lysosomes become dysregulated to sustain proliferative ...
Department of Chemical Sciences, Indian Institute of Science Education and Research, Kolkata, Mohanpur, Nadia, West Bengal 741246, India ...
The maturation of early endosomes into lysosomes is marked by a progressive decrease in interior (luminal) pH, which is crucial for the activation of resident enzymes that degrade exogenous ...
These mechanisms may serve as a checkpoint for the presence of the vacuole/lysosome. Animals, fungi and other eukaryotes have cells that are divided into sub-compartments that are called organelles.
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