Lubiprostone acts on type-2 chloride channels located on the apical side of gastrointestinal epithelial cells to promote electrolyte and fluid secretion into the small intestine and may also ...

Lubiprostone: Type 2 chloride channel (CCl2) activator. Chloride secretion in the intestinal lumen followed by passive diffusion of sodium and water. Nausea, headache.

There are actually two medications for IBS that are only FDA-approved for females: lubiprostone, which treats IBS with constipation, and alosetron, which treats severe IBS with diarrhea.

About this study. The purpose of this study is to determine if there are pyloric sphincter abnormalities in patients with gastroparesis symptoms and determine how prevalent these abnormalities are ...

We identified low to moderate certainty evidence that oral lubiprostone may result in little to no difference in treatment success and adverse events compared to placebo. Based on moderate certainty ...

Mounting evidence underscores the pivotal role of the intestinal barrier and its convoluted network with diet and intestinal microbiome in the pathogenesis of inflammatory bowel disease (IBD) and ...

Lubiprostone accelerated intestinal and colonic transit in healthy subjects,60 but had no significant effect on colonic motility or sensation61 in humans or smooth muscle in vitro.62 Lubiprostone may ...

About a month ago, I woke up without hearing in my left ear. I initially suspected a wax blockage or a blocked eustachian ...

A woman was arrested on Tuesday and charged with obtaining a controlled substance by fraud after she allegedly gave two prescriptions to a pharmacy in Hartselle under a different name, ...

Depending on your symptoms, other drugs may provide pain relief, such as lubiprostone, linaclotide, alosetron, and eluxadoline. Psychosocial therapy: Cognitive behavioral therapy (CBT) or hypnotherapy ...