Local anesthesia, as a mechanism of action, inhibits the nerves in question from passing their signals to the central nervous system. While patients do not feel pain in the area during a surgical ...

While the precise mechanism of action is unclear ... especially the central nervous and cardiopulmonary systems, local anesthesia has more confined, site-specific effects. Like general anesthesia ...

Their primary site of action is in the central nervous system, where they inhibit nerve transmission by a mechanism distinct from that of local anesthetics. The general anesthetics cause a ...

Despite the physiological importance of sodium channels and their possible role as general anesthetic targets, little is known about interaction sites or the mechanism of action. Penn's Roderic ...

Local anesthetics, such as novocaine ... so probably no single molecular mechanism of action exists for all anesthetics. Thus, the simple answer to the question of how anesthesia works is that ...

Simplifying assumptions such as the unitary hypothesis led early research on anesthesia to focus on nonspecific biophysical mechanisms. Reevaluation of the actions of anesthetics on a variety of ...

"Beyond suggesting a mechanism of anesthetic action, this discovery is of great clinical importance because it suggests that brain states under general anesthesia can be monitored using the EEG on ...

The research demonstrates a way to control the spread of the toxin and harness it into an effective local anesthetic that ... It is this exact mechanism that has attracted scientists looking ...

Lidocaine is a commonly used local anesthetic that works by blocking signals at the nerve endings in the skin. It is often used in the form of a topical cream or injection. However, recent ...

Liposomal bupivacaine was launched on the market 12 years ago to provide long-lasting local control of pain. The medication is used as a local anesthetic ... Its mode of action is based on ...