Treatments for uveitic macular edema, including systemic and local options, were among the topics debated at the Congress on Controversies in Ophthalmology.

Deaths from lidocaine poisonings more than doubled since 2010, calls to poison control centers suggested. Case reviews attributed increases in lidocaine poisonings to large doses administered in ...

A new study uncovers the long-elusive mechanism of inhalational anesthetics by identifying the RyR1 calcium channel as a key molecular target.

This is a new finding as previous studies have not demonstrated the relationship between RyR1 and anesthetic effects in mammals. A more detailed understanding of anesthetics' mechanism of action could ...

A more detailed understanding of anesthetics' mechanism of action could lead to the development of better anesthetics and treatment methods.

Its mechanism of action is akin to that of local anesthetics but demonstrates greater selectivity. AM404 holds potential for development as a pain-selective, peripherally acting analgesic, likely with ...

Uncovering a part of its mechanism of action Identification of RyR1 as a target molecule Since their anesthetic effects were discovered approximately 180 years ago, inhalational anesthetics have been ...

Since their anesthetic effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general anesthesia in surgical operations. However, the mechanism of their ...

The article describes the mechanism of action of DM199 (rinvecalinase alfa), a recombinant form of human tissue kallikrein-1, and its scientific rationale in the Company’s ongoing Phase 2/3 ...

The article describes the mechanism of action of DM199 (rinvecalinase alfa), a recombinant form of human tissue kallikrein-1, and its scientific rationale in the Company’s ongoing Phase 2/3 trial for ...

4 December 2024 - Capacity development goes beyond building skills. It is about empowering individuals and institutions to turn knowledge into sustainable action, innovation and resilience.

Children with any allergic history to any local anesthetic agents were excluded from the study. A total of 90 children who required administration of local anesthesia for their dental treatment were ...