Smith Department of Chemical Engineering ... was verified by the agreement between the bilayer structural properties (structure factor, bilayer thickness, and the area per lipid) and lateral diffusion ...

Andrew T. Lombardo, PhD, assistant professor of biochemistry, has received a $1.9 million National Institutes of Health grant to study cell polarity signaling.

The unfolded protein response (UPR) is a crucial signaling network that preserves endoplasmic reticulum (ER) homeostasis, impacting both health and disease. When ER stress occurs, often due to an ...

Lipid membranes, which form the outer layer of cells, can be engineered to influence cellular functions. For example, ...

The chemical structure of bacterial plasmalogens differs from that of mammals (see below). Plasmalogens are widely distributed within the mammalian organism. They are found in a variety of organs, ...

This fundamental study combines in vitro reconstitution experiments and molecular dynamics simulations to elucidate how membrane lipids are transported from the outer to the inner membrane of ...

For small-molecule drug development, the initial lead structure may be derived from modifications of the natural bioactive lipid (for example, using a steroid core, conformationally restricting a ...

This cryogenic molecular surface and interfacial ... to have contributed to advancing the understanding of lipid nanoparticle surface structures," said Kerry Benenato, Ph.D., Chief Platform ...

We report on the aggregation and dynamic behavior of excipients in type I and surfactant-free lipid formulations ... We performed molecular dynamics (MD) simulations using GROMACS 3.1.4 ...

Different phthalates have different chemical structures, which means they affect different processes within the body. And they might not operate in isolation. “You do need to study the effect of ...