lipids. The tunnel in the MLN64-START structure is just large enough to accommodate one molecule of cholesterol (Fig. 7). The size and hydrophobicity of the tunnel in the MLN64-START structure ...

This fundamental study combines in vitro reconstitution experiments and molecular dynamics simulations to elucidate how membrane lipids are transported from the outer to the inner membrane of ...

Scientists developed nanoparticles that respond to warmth inside tumors to boost ultrasound clarity, offering a safer and ...

This cryogenic molecular surface and interfacial analysis advance ... “At Sail Biomedicines, we are proud to have contributed to advancing the understanding of lipid nanoparticle surface structures," ...

This cryogenic molecular surface and interfacial ... to have contributed to advancing the understanding of lipid nanoparticle surface structures," said Kerry Benenato, Ph.D., Chief Platform ...

This cryogenic molecular surface and interfacial analysis advance ... “At Sail Biomedicines, we are proud to have contributed to advancing the understanding of lipid nanoparticle surface structures," ...

Oligosaccharyltransferase (OST) is a membrane-integral enzyme that catalyzes the transfer of glycans from lipid-linked oligosaccharides ... Here, we report the X-ray structure of a single-subunit ...

Lipid membranes, which form the outer layer of cells, can be engineered to influence cellular functions. For example, ...

The Hidden Language of GlycansImagine a vast molecular conversation happening within and between cells—where sugar-based structures act as sophisticated messengers carrying critical biological ...

Andrew T. Lombardo, PhD, assistant professor of biochemistry, has received a $1.9 million National Institutes of Health grant to study cell polarity signaling.

Global research shows how plankton adapt their cell membranes to survive changing ocean light, nutrients, and temperature.

Misfolded proteins thought to play a critical role in the progress of various neurodegenerative conditions could be prevented ...