Our aim was to examine the status of iron metabolism, lipid peroxidation and their subsequent relation with short-term clinical outcomes. We used malondialdehyde (MDA) concentration in the CSF as ...

MDA is the most mutagenic product of lipid peroxidation and is commonly used ... expression and a cytotoxic promoter of pathological pathways. Cancer cells have increased levels of reactive ...

The investigators then demonstrated that the dysregulation of this metabolic pathway led to increased lipid peroxidation—a process that damages cellular membranes and may trigger neuronal death.

It is mediated by iron molecules, with the cell dying through the degradation of the phospholipid bilayer by oxidation, a process called lipid peroxidation. However, recent studies have shown that ...

The mevalonate pathway (MVP) is a metabolic pathway that produces the building blocks for a wide range of biological molecules, from cholesterol to the long-chain lipid groups that anchor certain ...