Untargeted lipidomics analysis is widely performed using a variety of mass spectrometric methods. The original procedure, ...

Capstan Therapeutics scientists demonstrate that lipid nanoparticles can engineer CAR T cells within the body without laboratory cell manufacturing and ex vivo expansion. The method using targeted ...

"Interestingly, in cancer cells that are less susceptible to ferroptosis, lipid peroxidation occurred in the lysosomes, but this did not lead to lysosomal membrane damage," continues Yamada.

SAN DIEGO, March 12, 2025 /PRNewswire/ -- Avidity Biosciences, Inc. (Nasdaq: RNA), a biopharmaceutical company committed to delivering a new class of RNA therapeutics called Antibody Oligonucleotide ...

Many male reproductive pathologies and a part of undiagnosed infertility share an oxidative stress (OS) etiology with high reactive oxygen species and cytokine concentrations. The lack of reliable ...

Overall, this study elegantly highlights the importance of microglial lipid droplets in amyloid pathology and provides novel insights into their role in microglial function, lipid metabolism, and ...

Aims: Factors responsible for the progression of non-alcoholic fatty liver disease (NAFLD) to more severe liver injury are poorly understood. In the present study, we investigated the association ...

The new kit, which offers a preoptimized ionizable lipid mix for rapid payload screening and RNA drug delivery validation, complements the GenVoy-ILM product line, which includes reagents and off ...

Lipid peroxidation (LPO) occurs in response to oxidant attack, giving rise to unsaturated aldehydes as malondialdehyde (MDA), the main biomarker for LPO assessment. Levels of MDA are measured in ...

Soy protein isolate (SPI) was modified by lipid peroxidation product malondialdehyde (MDA), and the in vitro digestibility of modified SPI was investigated. Results indicated that incubation with ...

Insights from ACC 2024 by Dr Erin Michos reveals new paths in lipid management that address current treatment gaps.

Researchers determined through genetic and structural studies that it works by blocking transport of a lipid called lipopolysaccharide into place in the outer membrane.