In this important study, Kapoor et al, investigate the role of Wag31 in lipid and peptidoglycan biosynthesis in mycobacteria. A detailed analysis of Wag31 domain architecture revealed a role in ...

The American Society of Clinical Oncology, or ASCO, conference is just around the corner, but one subgroup of cancer researchers just had their own gathering, as breast cancer researchers came ...

Lipid nanoparticles, microscopic particles composed of lipids, are at the forefront of cutting-edge drug delivery technologies. These nanoparticles serve as carriers for drugs, vaccines, and other ...

Recall the Comirnaty® and Spikevax® mRNA-based vaccines each utilize lipid nanoparticles. The lipid nanoparticles include an mRNA “payload” encapsulated by a combination of four lipids ...

The penetration of PS nanoparticles into the lipid bilayer requires the removal of water molecules at the nanoparticle–membrane interface, which is an effective barrier to the entry of PSNPs into its ...

When formulating mRNA into lipid nanoparticles (LNP), various copy numbers of mRNA are encapsulated, leading to a distribution of mRNA loading levels within the LNPs. It is unclear whether the mRNA ...

Lipid-based Nanoparticles (LBNPs) have emerged as a transformative approach in cancer treatment, offering innovative drug delivery solutions that enhance therapeutic efficacy while minimizing adverse ...

The LNP Profiler with AutoLNP is set to become the new standard for lipid nanoparticle analysis in the biopharma sector, supporting the rapid advancement of next-generation therapeutics. Press Release ...

This unique property facilitates membrane fusion-mediated endosomal escape ... phospholipids hold great promise for developing lipid nanoparticles (LNPs) used in mRNA vaccines, cancer treatment ...