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Activation of the AMP-dependent kinase pathway and subsequent increased fatty acid oxidation seems to be the main mechanism of action of these hormones in the regulation of lipid metabolism.
A group at MedUni Vienna has identified a regulatory loop controlled by leptin, by which this adipocyte-derived hormone ... new lipids, thereby reducing liver fat content. This effect was ...
They have developed a new compound, ZTA-261, which selectively binds to the thyroid hormone receptor beta (THRβ). THRβ plays an important role in the regulation of lipid metabolism, which ...
These are hormones derived from fats or lipids such as linoleic acid, arachidonic acid and the phospholipids. The main class of lipid-derived hormone is the steroids which are derived from ...
"The dogma in the steroid receptor field for 50 years has been that only receptors located in the nucleus respond to steroid hormones by regulating ... mice suppresses all lipid synthesis.
Palmitoleate is the first lipid demonstrated to work as a hormone, a job usually done by proteins, such as insulin, or by small molecules, such as adrenaline. If the lipid works the same way in ...
Thyroid hormones regulate metabolic rate and lipid metabolism. They influence the expression of genes involved in lipid synthesis, uptake, and degradation in the liver. Hypothyroidism is ...
Working backwards, the researchers then looked at what could be triggering the specific immune cells to release these lipids, and the culprit seemed to be a type of stress hormone called ...
This shows how immune cells can be influenced by modifications to the lipid-dependent pathway. As well as identifying a new molecular mechanism in the immune system, the data highlights a ...
Scientists at the University of Pittsburgh have discovered a predictor of blood lipid — or cholesterol — status for midlife women that may be key to understanding how hormone replacement ...
Researchers have developed a new compound, ZTA-261, that binds to thyroid hormone receptor beta (THR ). THR plays an important role in the regulation of lipid metabolism, which affects lipid ...