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Findings uncover new mechanism linking cohesin complex to gene regulation
Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA ...
C&EN4d
The Use of Solid Supports to Generate Nucleic Acid Carriers
Nucleic acids are the foundation stone of all cellular processes ... and yields over comparable solution methodologies and facilitate the development of structure activity relationships. We also ...
Nature10d
Nucleic-acid therapeutics articles from across Nature Portfolio
Nucleic acid therapeutics are based on nucleic acids or closely related chemical compounds. They include antisense oligonucleotides, aptamers and small interfering RNAs, and are typically ...
PNAS25d
Structure and nucleic acid interactions of the SΔ60 domain of the hepatitis delta virus small antigen
Financial support from the Agence nationale de recherche sur le sida et les hépatites virales (ECTZ158948 to A.B. and ECTZ143165 to M.L.) and the China Scholarship Council (202008620095) is gratefully ...
C&EN29d
Lewis Acid-Catalyzed Domino Inverse Electron-Demand Diels–Alder/Thermal Ring Expansion Reaction for the Synthesis of Arene-Annulated Eight-Membered Nitrogen Heterocycles
Institute of Organic Chemistry, Justus Liebig University Giessen, 35392 Giessen, Germany Center for Materials Research (LaMa), Justus Liebig University Giessen, 35392 Giessen, Germany Institute of ...
Frontiers29d
Predictive value of systemic inflammatory index (SII) for the time to negative nucleic acid conversion in patients with mild COVID-19 by the omicron wave
The definitive impact of inflammatory indices on forecasting the period required for a negative shift in nucleic acid status during the Omicron wave remains ambiguous. This research endeavors to ...