Effector cells primarily undergo aerobic glycolysis, while memory cytotoxic T-cells exhibit enhance OXPHOS and fatty acid oxidation. Chronic infection or tumorigenesis impairs major metabolic ...

Exhausted T cells: Researchers map genome-wide changes that drive T cell maturation and exhaustion. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2016 / 12 ...

Prof. LIANG Xingjie's team from the National Center for Nanoscience and Technology, along with Prof. GONG Ningqiang from the University of Science and Technology of China, has developed a biomimetic ...

Minerva Biotechnologies - Overcoming the Solid Tumor Barrier: MUC1*-Targeted CAR T bearing 1XX mutations overcomes exhaustion and enables killing of low antigen expressing cancer cells ...

T cells that encounter too many tumor cell pieces can also become exhausted and lose their ability to kill cancerous cells. The researchers showed that removing Asxl1 prevented T-cell exhaustion ...