Diagram of an antibody structure showing its key components, including antigen binding sites, variable and constant regions, light chains, and heavy chains. Image Credit: aiyoshi597/Shutterstock.com ...

Antibody structure prediction has been widely used in many biological analyses 16,17,75. As example applications of the PIGS protocol, we have applied the PROCEDURE above to the modeling of the ...

Immunoglobulin G4 antibodies exhibit unusual properties with important biological consequences. We report the structure of the human full-length IgG4 S228P anti-PD1 antibody pembrolizumab, solved ...

The structure of the teleost Immunoglobulin M core provides insights on polymeric antibody evolution, assembly, and function. Nature Communications, 2023; 14 (1) DOI: 10.1038/s41467-023-43240-z; ...

More information: Mengfan Lyu et al, The structure of the teleost Immunoglobulin M core provides insights on polymeric antibody evolution, assembly, and function, Nature Communications (2023). DOI ...

Confocal microscopy image of human embryonic kidney cells. Nanoparticles filled with human immunoglobulin were delivered to the cells. The cell nucleus is blue, endosomes (which sequester ...