Figure 1: Schematic of RAG-mediated DNA binding and cleavage. Here we report the crystal structure of the mouse ... experiments comparing fluorophore-labeled and control substrates demonstrated ...

In an effort to understand the functional role of the SWIRM domain in chromatin remodeling and gene transcription, we report here the first three-dimensional solution structure of the SWIRM domain ...

But the Nobel Foundation only awarded three scientists for the discovery of DNA’s structure: James Watson, Francis Crick, and Maurice Wilkins. Since 1869, scientists had known about DNA ...

A piece that aired on NPR this week about the discovery of DNA's structure neglected to mention the significant contribution of Rosalind Franklin to that scientific milestone. And now some ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...

The MEILB2 protein sandwich carries the BRCA2 protein precisely to the DNA break points. To determine the structure of this BRCA2 complex, the researchers used X-ray crystallography. In this ...

Scientists James Watson and Francis Crick were famously the first to work out the structure of DNA, and Rosalind Franklin and Maurice Wilkins are often credited for capturing the images of the ...

Mark Lorch does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond ...

In a leap forward for genetic and biomedical research, two scientists at the University of Missouri have developed a powerful ...

When you know how to look at it, this shadowy X-ray photograph speaks volumes about the shape of DNA. Explore the image using our guide.