The ability of protein kinases to transfer a phosphate group to target proteins plays an important role in many cellular ...

Comparison with various high-throughput phosphorylation mapping studies showed limited overlap between the kinase phosphorylation interactions and kinase protein–protein interactions, suggesting ...

Although the function of the p42/p44 mitogen-activated protein (MAP) kinase pathway in long-term potentiation at hippocampal CA3–CA1 synapses has been well described, relatively little is known ...

This leads to recruitment of the kinase to the membrane and initiation of its activation via complex mechanisms involving Ca 2+ -binding (for Ca 2+ -dependent PKCs) and regulatory phosphorylation ...