High-risk human papillomavirus (HPV)-related oropharyngeal squamous cell carcinomas have a more favorable prognosis than HPV-negative ones. p16 immunohistochemistry has been recommended as a ...

We report our experience with p16, p53 and HPV ISH (types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58 and 66) in determining the aggressive nature of this carcinoma. Methods: A tissue microarray (TMA) ...

Squamous-cell carcinoma is one of the most common cancers in humans. Most cases are localized and treatable; the small percentage that recur or spread can be fatal. Immunocompromised patients are a ...

Surgery is a mainstay treatment for head and neck squamous cell carcinoma (HNSCC). However, the clinical challenge is to ...

There were no statistically significant differences in clinical characteristics including sex, age, smoking history, TNM stage and treatment modalities between HPV-positive and -negative patients. The ...

It is best to seek treatment for squamous cell carcinoma (SCC) as early as possible, as doctors can usually treat early stage SCC easily. Read more here.

Resectable locally advanced head and neck squamous-cell carcinoma (HNSCC) is a burdensome disease with few treatment advances in recent decades.