Interferon-gamma—an immune response–stimulating signaling molecule—helps activate the immune system to recognize and attack cancer cells.

Researchers have discovered that the interferon gamma receptor (IFNgR) signaling pathway is critical for susceptibility of glioblastoma tumors to killing by CAR T-cell immunotherapy.

Researchers at Massachusetts General Hospital (MGH) have discovered that the interferon gamma receptor (IFNgR) signaling pathway is critical for susceptibility of glioblastoma tumors to killing by ...

UCLA researchers shed light on how interferon-gamma (IFN-y) guides the treatment response in people with advanced melanoma who are treated with one of the leading immunotherapies -- immune ...

In mice with an intact immune system, alpha-synuclein overexpression in the mouse model resulted in increased numbers of CD4+ T-cells that were also positive for the transcription factor T-bet, along ...

André Ballesteros-Tato, Ph.D., and colleagues at the University of Alabama at Birmingham have now published a mouse-model study in the journal Immunity showing that interferon-gamma produced by T ...

Rheumatology > General Rheumatology Interferon Blocker Crushes Macrophage Activation Syndrome — Small trial shows promise for treating life-threatening complication of rheumatic diseases ...

In a new study, researchers compared serum cytokine expression among healthy individuals and those with PASC [post-acute sequelae of coronavirus disease 2019 (COVID-19)].