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Ozempic-maker Novo Nordisk on Friday ousted its CEO Lars Fruergaard Jorgensen over concerns the company is losing its first-mover advantage in the competitive obesity drug market to American rival ...
The N-terminus of the B-chain of insulin may adopt two alternative conformations designated as the T- and R-states. Despite the recent structural insight into insulin–insulin receptor (IR) complexes, ...
Technosphere insulin, a rapid-acting human insulin administrated through an inhaler, was associated with reductions in HbA1c at 30 weeks for adults with type 1 diabetes, according to findings from ...
The FDA has approved Merilog, a new fast-acting insulin biosimilar for managing blood sugar in people with diabetes, marking the first such biosimilar to receive federal approval.
Keywords: neprilysin, NEP inhibitor, structure-activity relationship, drug design, clinical Citation: Zhang X, Hu C, Tian E, Shen Y, Liu W and Li J (2024) Comprehensive review on neprilysin (NEP) ...
Profluent’s latest protein language model incorporates structural and functional context to decode the language of biology for fine-tuned protein design.
In this paper, a micro-needle array combined with transdermal delivery, as well as the detection of micro-sensors intelligent transdermal insulin delivery systems was designed with characteristics of ...
Insulin's structure varies slightly between species of animal. Both porcine (from pigs) and bovine (from cows) insulin are similar to human insulin but porcine insulin resembles human insulin more ...
Australian scientists have designed a new capsule that could mean diabetics might one day swallow their insulin instead of injecting it. The design also has potential uses for delivering other ...
Diabetes used to be invariably fatal, killing people by disrupting sugar metabolism until scientists successfully found an effective treatment. Millions have been treated with insulin since the 1920s.
In an ideal world, managing diabetes wouldn’t involve insulin injections but would be as simple as popping a pill. Now a team of scientists has demonstrated an oral tablet that’s self ...
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