It is clear that to progress in the design of insulin or IGF1 mimetics or antagonists, obtaining a high-resolution structure of the ligand–receptor complex will represent a quantum leap that ...

While the structure of this complex protein ... messages into the cell we will be in a better position to design compounds that mimic insulin and could be used to treat diabetes.” ...

Australian scientists revealed the structure of the major part ... the cell we will be in a better position to design compounds that mimic insulin and could be used to treat diabetes." ...

By demonstrating how the shape of DNA can affect insulin gene function ... target best—a process called rational design. As the first crystal structure of this type, the researchers say it ...

A global team of researchers from Cleveland, Australia, Chicago, India and Oregon has made a discovery about insulin and its structure that promises to enable design of new insulin products that will ...

Australian scientists revealed the molecular structure of a hitherto unknown ... cell we will be in a better position to design compounds that mimic insulin and could be used to treat diabetes.” ...

By demonstrating how the shape of DNA can affect insulin gene function ... target best – a process called rational design. As the first crystal structure of this type, the researchers say ...

The insulin-like growth factor 1 (IGF1 ... We have determined the 2.1 Å-resolution crystal structure of the tris-phosphorylated form of IGF1RK in complex with an ATP analog and a specific ...

Our research interest is in the development of ultra-stable insulin analogs. Insulin's instability lies in its enhanced susceptibility to chemical degradation and formation of insoluble fibrils ...

Australian scientists revealed the structure of the major part ... the cell we will be in a better position to design compounds that mimic insulin and could be used to treat diabetes." ...

A global team of researchers from Cleveland, Australia, Chicago, India and Oregon has made a discovery about insulin and its structure that promises to enable design of new insulin products that ...