In diabetes, much attention goes to sugar control, insulin levels, and the threat of nerve damage. But a new study reveals ...

Diabetes Mellitus is a chronic metabolic disorder and is one of the leading chronic diseases worldwide. It is widely known for its impact on blood ...

Researchers uncover how diabetic peripheral neuropathy weakens bones via disrupted cellular communication using mouse models ...

Peptides have emerged as a fascinating area of scientific inquiry due to their potential to modulate various physiological ...

Breast cancer is the most commonly diagnosed cancer among women worldwide and represents a major public health concern due to ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes.

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study. Blocking ...

Baxter, R.C. (2023) Signaling Pathways of the Insulin-Like Growth Factor Binding Proteins. Endocrine Reviews, 44, 753-778.

Elevated leptin levels trigger insulin resistance by activating pro-inflammatory pathways that induce mitochondrial dysfunction and oxidative stress, both implicated in T2DM.

The insulin-like growth factor (IGF) receptor signaling pathway plays a crucial role in regulating growth, development, and metabolism in the human body. It encompasses a group of signalling molecules ...

Local autocrine plasticity signaling in single dendritic spines by insulin-like growth factors The insulin superfamily of peptides is essential for homeostasis as well as neuronal plasticity, learning ...