Two well known factors are tumor hypoxia and overexpression of epidermal growth factor receptor (EGFR), a molecule that triggers signal pathways to regulate cell growth and contribute to oncogenesis.

Kym-1 rhabdomyosarcoma growth depends on functional insulin/IGF signal pathways In conclusion, although the specific signal molecules within the TNF pathway responsible for interference with ...

Learn 7 terrifying ways sugar consumption feeds cancer cells and accelerates tumor growth. Discover how your daily sugar ...

BACKGROUND: Recent studies have highlighted the deleterious role of high phosphate intake in hypertension by means of ...

These pathways include nuclear factor- B, p38 mitogen-activated protein ... levels leads to both insulin resistance and impaired insulin secretion. Therefore, we propose here that the ...

Insulin-like growth factor 1 (IGF1) is a polypeptide hormone structurally ... It activates both the mitogen-activated protein (MAP) kinase and PI3K signaling pathways, acting in almost every tissue in ...

Growth Hormone-Releasing Peptide-2 (GHRP-2) is a synthetic hexapeptide that has garnered significant attention in the ...

Abstract:        Obesity, a growing global issue, has been closely associated with an increased risk of various cancers, especially breast cancer. El ...

A common fatty acid in olive oil, as well as many other plant oils, has been found to stimulate the body's production of new ...

Thus, in HR + /HER2 + breast tumors a vicious cycle is established between ER genomic and non-genomic mechanisms of action and the growth factor ... therapy ER/GF signaling pathways and ...

When the workload on the heart increases, the ventricular wall may thicken too, known as cardiac hypertrophy. This is an adaptive response that reduces pressure on the heart and maintains the activity ...

Scientists at Tohoku University Graduate School of Medicine have identified colonic inflammation as a previously unrecognised ...