In a leap forward for diabetes research, researchers reveal that the feel-good hormone, dopamine, regulates insulin secretion through a heteromeric complex of receptors, thereby providing new ...

In a leap forward for diabetes research, Tokyo Tech researchers reveal that the feel-good hormone, dopamine, regulates insulin secretion through a heteromeric complex of receptors, thereby ...

Microtubules -- cellular 'highways' that deliver cargo to the cell membrane for secretion -- have a surprising role in pancreatic beta cells. Instead of facilitating glucose-stimulated insulin ...

Between 2016 and 2022, the researchers measured insulin secretion in response to carbohydrates (glucose), proteins (amino acids), and fats (fatty acids) from pancreatic islet cells taken from 140 ...

The research group is currently carrying out a mapping of microRNAs that may be involved in the secretion of insulin in type 2 diabetes. This knowledge is of importance in the development of ...

Methods Stimulated C-peptide secretion was assessed using the mixed-meal tolerance test in patients with LADA (n = 32), type 1 diabetes mellitus (n = 33) and type 2 diabetes mellitus (n = 30 ...

In addition, 5-PAHSA restores normal pulsatility of insulin secretion in islets from persons with type 2 diabetes. 42,57–59 Not all studies 60,61 have shown these beneficial effects of PAHSAs.

Circumstances are different when it comes to neurally mediated insulin secretion: "The smell and sight of a meal stimulate specific immune cells in the brain known as the microglia," says study ...

Researchers from Osaka Metropolitan University have identified a gene that, when activated by metabolic stress, damages pancreatic β-cells—the cells responsible for insulin production and blood sugar ...

More information: Fumiya Uefune et al, Dopamine Negatively Regulates Insulin Secretion Through Activation of D1-D2 Receptor Heteromer, Diabetes (2022).DOI: 10.2337/db21-0644 ...