Koby Baranes, PhD, head of science at Clock Bio, cautions, “Aging is not yet fully understood and existing models often fail ...

The spark came in 2006, when Yamanaka Shinya, Takahashi’s colleague at Kyoto University, reprogrammed ordinary skin cells into induced pluripotent stem cells (iPSCs) – capable of morphing into ...

In this instance, the cells were derived from induced pluripotent stem cells rather than from embryonic stem cells like BlueRock’s candidate. The results, however, were very similar. In the study, ...

Shinya Yamanaka, a professor at Kyoto University in Japan who won the Nobel Prize in Physiology or Medicine in 2012. He pioneered the induced pluripotent stem cell (iPSc) technology that converts ...

In order to turn adult cells back into pluripotent stem cells, scientists typically use viruses to insert four genes — Sox2, Oct4, Klf4, and cMyc — into the cells.

We could potentially repair or replace tissues with an effectively infinite supply of a patient's own cells. Although the Nobel Prize for induced stem cells was handed out over a decade ago, the ...

Here we describe unicellular Sox and POU factors. Choanoflagellate and filasterean Sox proteins have DNA-binding specificity similar to mammalian Sox2. Choanoflagellate—but not filasterean—Sox can ...

The study, published Sep. 10 in Stem Cell Reports, used human induced pluripotent stem cells ... reprogramming,” in which mature cells can revert to their embryonic pluripotent status — a technique ...

The prize also recognizes Gladstone Senior Investigator Shinya Yamanaka, MD, PhD, who received a Nobel Prize in 2012 for his discovery of induced pluripotent stem cells (iPS cells), which are ...

By adding just 4 genes to adult skin cells, they became like embryonic stem cells, which can produce any type of cell in the body. He called them induced pluripotent stem (iPS) cells and won the Nobel ...

T he 2022 Nobel Prize in Chemistry goes to two researchers who pioneered a new way of assembling large molecules, known as click chemistry, and one who applied that principle to probe the workings of ...