MedPage Today on MSN1d
Myasthenia Gravis Antibody Types
Myasthenia gravis (MG) results from autoimmune antibodies against the post-synaptic neuromuscular junction with three major ...
C&EN1mon
Multilayer Adjuvanted Influenza Protein Nanoparticles Improve Intranasal Delivery and Antigen-Specific Immunity
Intranasal vaccination is a desired route for protection against influenza viruses by mucosal and systemic immunity. However, the nasal mucosa impedes the intranasal delivery of vaccines. Here, we ...
eLife1mon
A delta-tubulin/epsilon-tubulin/Ted protein complex is required for centriole architecture
The study by Pudlowski et al. shows that a previously-identified protein complex, composed of delta- and epsilon-tubulin together with TEDC1 and TEDC2, functions in generating centriolar triplet ...
Frontiers6y
Sialylated Autoantigen-Reactive IgG Antibodies Attenuate Disease Development in Autoimmune Mouse Models of Lupus Nephritis and Rheumatoid Arthritis
Subsequently, the cells were cultured in 96-well plates with ICs containing 10 µg of chicken Col II and different proportions of non-sialylated (<1% sialylation) and sialylated (46% sialylation) Col ...
Frontiers7y
Mucosal Administration of Cycle-Di-Nucleotide-Adjuvanted Virosomes Efficiently Induces Protection against Influenza H5N1 in Mice
In this range, the IgG, IgG1, IgG2a, IgG2b, and IgG3 titers significantly increased compared to the antigen alone group, but with only little differences between the groups receiving reduced antigen ...
eLife8y
Lineage tracing of human B cells reveals the in vivo landscape of human antibody class switching
Antibody class switching is a feature of the adaptive immune system which enables diversification of the effector properties of antibodies. Even though class switching is essential for mounting a ...