UPDATE: I-65 reopened early Tuesday morning. An explosion and semi-truck fire in northwest Indiana has closed a section of Interstate 65, police said. Stream NBC 5 for free, 24/7, wherever you are ...

MERRILLVILLE, Ind. (STMW) --The Indiana Department of Transportation has reopened Interstate 65 between U.S. 30 in Merrillville and Lafayette, but is urging "extreme caution" when traveling on ...

Concrete restoration work on I-65 between U.S. 231 and the I-80/94 interchange will result in lanes and ramp closures through the fall, according to the Indiana Department of Transportation.

Interstate 65 rings the bell at No. 12, with 36.5 deaths per 100 miles. I-65 is 887 miles from Gary to the Gulf Coast and had 324 deaths during the period. But Indiana’s share of risk is not ...

To INDOT's credit, minutes after this I-65 closure, roadside message boards south of Indianapolis started touting I-74 routes to Chicago. If there's anyway to turn up the volume on that message on ...

GARY, Ind. (STMW) - A car struck a Chicago woman wearing lingerie who was walking on I-65 Saturday morning, seriously injuring her near Gary, Indiana. The pedestrian was identified as Channing ...

Lanes were closed on I-65 in northwest Indiana Friday morning and lengthy delays were expected after a cattle truck carrying more than 100 cows overturned, according to the Indiana State Police.

Chicago man dies after stolen Maserati slams into pole in NW Indiana ... The crash happened about 12:45 a.m. on the I-65 exit ramp to Ridge Road in Gary, state police said.

COLUMBUS — A Chicago, Illinois woman was arrested Sunday after a vehicle pursuit on I-65 in Jackson and Bartholomew counties. At about 5:15 p.m., Trooper Bryce Potraffke was patrolling I-65 near ...

SCOTTSBURG, Ind. (WISH) — A Chicago man was arrested Monday after a chase that covered Scott, Jackson and Bartholomew counties along I-65 between Louisville, Kentucky, and Indianapolis, Indiana ...

SCOTTSBURG, Ind. (WISH) — A Chicago man was arrested Monday after a chase that covered Scott, Jackson and Bartholomew counties along I-65 between Louisville, Kentucky, and Indianapolis, Indiana ...

Mekyell Brown-Champion, 25, is accused of robbing the gas station in Scott County around 8 a.m. on Feb. 10. Seymour Police say they spotted and started chasing Champion’s car on I-65 North near ...