A new study published in Nature Neuroscience has identified a brain circuit in mice that overrides basic needs like hunger or social contact in favor of seeking safety. Researchers found that a ...

A high-fat diet can promote overweight and increase the risk of metabolic diseases, such as diabetes. In mice brains, this leads to measurable changes in the region of the hypothalamus. However ...

The hypothalamus is a small but crucial part of the brain. ... A 2017 study in mice found that eating a high fat diet led to inflammation of the hypothalamus. On the other hand, ...

To test the theory, the team genetically eliminated Ppp1r17 in the hypothalamus of three-month-old mice—roughly the age of a teenager. Within two months, the critters blew up in size. They began ...

One route they are studying involves supplementing mice with eNAMPT, the enzyme produced by the fat tissue that returns to the brain and fuels the hypothalamus, among other tissues.

Researchers have discovered the mechanism by which a cluster of astrocytes, specialized brain cells, in the hypothalamus cause obesity in mice. Their findings could lead to a new obesity treatment ...

A new study in mice proposes for the first time a novel factor that drives aging processes. The authors of the study report that a reduction in the protein menin in the brain’s hypothalamus ...

One route they are studying involves supplementing mice with eNAMPT, the enzyme produced by the fat tissue that returns to the brain and fuels the hypothalamus, among other tissues.

Neurons whose activity mirrors fighting by other mice were identified in the male mouse hypothalamus and were functionally important for aggression.

Risk preferences in mice are linked to distinct hypothalamus–habenula circuits. The lateral habenula (LHb) neurons show activity reflecting individual risk preferences before action selection.

When the scientists directly stimulated the Substance P neurons in the pre optic hypothalamus, the male mice that had just completed mating behaviors were driven to immediately resume sexual activity.

After exploring a number of possible causes, lead author Christophe Galichet compared the microbiome – bacteria, fungi and viruses that live in the gut – in the mice from the Crick and mice ...