A new study published in Nature Neuroscience has identified a brain circuit in mice that overrides basic needs like hunger or social contact in favor of seeking safety. Researchers found that a ...

Diffusion-based manifold approximation and projection (dbMAP) embedding of 51,623 single-cell transcriptomes of the mouse hypothalamus from three different studies, colored by their annotated ...

To test this hypothesis, Dr. Jineun Kim (KAIST Ph.D. graduate, now at Caltech) demonstrated during her doctoral research that ...

Young mice fed a high-fat diet developed obesity, showed anxiety-like behavior, and had distinct brain signaling and microbiome patterns compared to their lean counterparts. These findings suggest ...

Maintaining a stable body temperature is essential for survival. Animals, including humans, use both autonomic processes -- such as shivering or activating brown fat -- and behaviors -- such as ...

In animals with social structures, the drive to reproduce is a complex process; governed by the brain, it's influenced by both internal cues such as ...

A 2023 study in mice showed that genetic control of insulin production by the choroid plexus could change food intake. The hypothalamus was rewired by changing choroid plexus insulin levels.

A common microbe, found in yogurt, could improve mothers' moods after birth, research suggests—potentially helping ward off ...

We report here that the delivery of leptin to the hypothalamus through intracranial gene transfer results in the efficient normalization of body weights in obese mice, using doses of recombinant ...