Infuzide was identified through whole cell-screening of 17 newly synthesized hydrazone-based molecules—an effort led by interdisciplinary teams at the University of Toulouse in France and the ...

The libraries are constructed using consecutive on-bead chemical synthesis and DNA encoding ligations, resulting in decodable library beads. Anjali Dixit Brian M. Paegel ...

To address this, herein, we illustrate a short and easy synthesis of hydrazide–hydrazone-based library. Screening of the library members in colon cancer cell lines (HCT-116, DLD-1, and SW-620) yielded ...

Synthesis and characterization of the hydrazone compounds . HL1-HL13 . Syntheses. A mixture of the respective arylamine (6.63 mmol), water (3.5 mL) and concentrated HCl (3.5 mL) was stirred until ...

Dr. Robert Anthony Holton, known as “Bob” to friends and colleagues, was a groundbreaking chemist and the scientist behind the first total synthesis of the cancer drug Taxol. He died ...

A series of new organic nonlinear optical nitrophenylhydrazone crystals based on pyrrole with various substituents (X: -H, -CH3, -CF3) on the hydrazone group (–CX═N–NH–) has been synthesized and their ...