INmune Bio's XPro1595 targets soluble TNF for Alzheimer's. Phase 2 results could reshape inflammatory disease treatment.

Chloride intracellular channel-4 (CLIC4) is regulated by p53 and tumor necrosis factor-α (TNF-α), it is linked ... with bovine serum albumin was used as negative control and human melanoma tissue ...

Objective To assess the effects of treatment with antitumour necrosis factor (TNF) agents, methotrexate, or other non-biological disease-modifying antirheumatic drugs (DMARDs) on cardiovascular event ...

The following oligonucleotides were used for TNF-α: forward primer, 5′-GGTGCTTGTTCCTCAGCCTC-3′; reverse primer, 5′-CAGGCAGAAGAGCGTGGTG-3′; and the probe Fam 5′-TCCTTCCTGATCGTGGCAGGCG-3′ Tamra. For ...

Methods Vascular 18F-fluciclatide binding was evaluated using ex vivo analysis of carotid endarterectomy samples with autoradiography and immunohistochemistry, and in vivo kinetic modelling following ...

The addition of tumor-necrosis factor-α (TNF-α) to this treatment approach has changed the situation dramatically. High response rates and limb-salvage rates have been reported in multicenter ...

Abstract: Accurate and real-time monitoring of biomarker proteins, such as Tumor Necrosis Factor (TNF) alpha, plays a vital role in early disease diagnosis, effective treatment design, and ...

Objective To identify predictors of response to tumor necrosis factor (TNF) antagonists in ankylosing spondylitis (AS) and psoriatic arthritis (PsA). Methods Systematic review and meta-analysis of ...

The actions of cytokines are oftentimes redundant and pleiotropic, and the same occurs with tumor necrosis factor-alpha (TNF-α ... IL-6 is present in normal human skin and is immunologically detected ...

Tumor necrosis factor alpha (TNF-α) has been a central focus in immunology for over three decades. ... TNF-α Across Species: Human and Animal Health in Parallel .