Fragile X disorders include two distinct conditions: fragile X syndrome (the most common single-gene cause of developmental delay and autism) and an entirely separate group of premutation syndromes.

HLA allele loss of heterozygosity detection analysis was performed using LOHHLA 27 which is the only software tool available for HLA class I allele loss of heterozygosity detection.

Iberia Airlines will invest approximately $6.9 billion into its flight operations. The airline will also increase flights to Spain from Philadelphia and recently began a new route from Orlando ...

Gene flow, anticipated (He) and observed heterozygosity (Ho), degree of genetic diversity and Hardy-Weinberg equilibrium (HWE) were determined. The results revealed that for Red Sokoto and West ...

Perhaps, skeptics have suggested, the observed fluctuations in allele frequencies are just routine oscillations of variants in the gene pool rather than proof positive of natural selection acting ...

The Good Life: Can Certain Audio Frequencies Help you Focus? Editor's note: This is a preview of The Good Life, Newsweek's weekly newsletter with tips and stories on lifestyle, health ...

FORE Biotherapeutics, a registration stage biotherapeutics company dedicated to developing targeted therapies to treat patients with cancer, today presented ...

FORE Biotherapeutics Presents New Plixorafenib Results at AACR 2025 Demonstrating Pharmacodynamic Effect in Clinical Tumor Biopsies and Decreased V600E Mutant Allele Frequency in ctDNA of 85% of ...

Allele-specific HLA LOH frequencies and survival outcomes in cancer: a real-world analysis [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2025; Part 1 ...

A comprehensive atlas maps DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation.

A notable outcome in the model is that expected allele frequency (and in turn expected heterozygosity) is constant with respect to sampling breadth. The result also holds empirically across several ...