Researchers at Shanghai Jiao Tong University have produced fertile adult mice from embryos constructed entirely with male ...

The complex nature of mutagenesis gives rise to diverse mutation spectra (frequency and distribution), characterized by distinct types, rates, and distributions of single and multi-nucleotide ...

Highly sensitive and accurate methods are needed to define target allele frequencies (AFs) in next-generation sequencing (NGS) reference material which is critical for the development and ...

A phased genome of the highly heterozygous ‘Texas’ almond uncovers patterns of allele-specific expression linked to heterozygous structural variants Article Publication Date 9-Apr-2024 ...

Cancellieri et al. 11 described an allele-specific off-target site created by a variant that occurs at an allele frequency of 6% in persons of African ancestry. We had independently nominated this ...

Purpose Normal-appearing breast epithelium can contain genetic abnormalities, including allele imbalance (AI), also referred to as loss of heterozygosity. Whether abnormalities are associated with ...

We calculated ROH on the basis of the recommendations of Howrigan et al. (2011) by first removing all SNPs with a minimal allele frequency of 5% (MAF 0.05) and performing a “moderate SNP pruning” ...

Allele frequency is a measure of the relative frequency of an allele on a genetic locus in a population. Usually it is expressed as a proportion or a percentage. In population genetics, allele ...

The HLA allele frequency data for world populations were obtained from the Allele Frequency Net Database . Statistical analyses were performed using SPSS program v. 17.0 and STATISTICA v.6.1 StatSoft ...

What you need to know about 5G frequencies. At its highest speeds, 5G should be able to reach as much as about 2 gigabits per second (Gbps) — two orders of magnitude faster than LTE, which tops ...