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One of the main factors determining therapeutic antibodies’ half-life is the interaction between the antibody’s Fc region and ...
The protein language model is trained solely on paired human antibody sequences with scalable applications in antibody engineering and optimization.
Debates over AI antibody design terminology have clouded the industry’s shared mission of bringing better therapeutics to the clinic faster.
abstract-Functionalizing chemotherapeutics-loaded liposomes with monoclonal antibodies can enhance their specificity and minimize side effects. Targeting the human epidermal growth factor receptor 2 ...
Engineering antibodies with a novel fusion protein Fusing two immune system proteins leads to a new method of generating antibodies, opening opportunities for advancing drug discovery Date: March ...
Herceptin (trastuzumab) has since served as one of these game-changing therapies and is an antibody which is directed towards HER2. The agent works by blocking HER2 signaling to "shut off" the cancer ...
Antibody-drug conjugates have had a tremendous impact on breast cancer care and treatment, according to Dr. Charles E. Geyer.
Trastuzumab Challenged Claim Types in IPR and Litigation: Claims include those challenged in litigations and IPRs. Claims are counted in each ...
Tanvex Biopharma Inc. said its U.S. subsidiary, Tanvex Biopharma U.S.A. Inc., received an FDA complete response letter (CRL) on Jan. 3 for its TX-05 BLA, a biosimilar that references Roche AG’s ...