Mammary gland fibroblasts are highly plastic and transition through distinct states during development and disease. A new ...

In recent years, the treatment landscape of HR+/HER2−ve breast cancer has completely changed with the introduction of particularly active targeted drugs, from CDK4/6 inhibitors, mTOR inhibitors, and ...

Zymeworks' financial stability is evident with $76.3 million in revenue in 2024 and a cash runway extending through late 2027 ...

Numerous studies conducted by researchers at Dana-Farber Cancer Institute report progress for cancers including head and neck cancer, metastatic breast cancer and lung cancer.

The frequency of high blood glucose among patients receiving PI3K/Akt inhibitors to treat breast cancer has some oncologists ...

Cancer patients invariably develop resistance to targeted drugs, so drugmakers develop strategies to combat it before ...

In the Phase III SELECT-GCA trial, Rinvoq (upadacitinib) 15 mg with a 26-week glucocorticoid taper significantly improved ...

Simultaneously, the Wnt/β-catenin signaling pathway is abnormally activated, resulting in increased expression of VEGF and VEGF2-factors associated with angiogenesis. This further promotes the ...

“With the majority of breast cancer cases historically considered HR positive, HER2 negative, additional treatment options are needed to improve outcomes for patients with metastatic disease that ...

This symptom could be easily dismissed as a sign of a cold or the flu but it could signal something far more ... be a red flag sign of a deadly cancer. The expert urged people to seek medical ...