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Yenamandra, A. and Marjoncu, D. (2020) Voxelotor A Hemoglobin S Polymerization Inhibitor for the Treatment of Sickle Cell Disease. Journal of the Advanced Practitioner in Oncology, 11, 873-877.
A breakthrough in the understanding of how mammals create red blood cells could lead to opportunities for artificial blood to ...
Summary: This study investigates the hypoxia rescue mechanisms of neurons by non-neuronal cells in the brain from the perspective of exosomal communication between brain cells. Through multi-omics ...
Gliadin and glutenin proteins with 10, 20, 30 and 40% of glycerol were compression molded into films (130 °C) and evaluated for protein polymerization, β-sheet structure and nano-structural morphology ...
In people with sickle cell disease, abnormal hemoglobin molecules - hemoglobin S - stick to one another and form long, rod-like structures. These structures cause red blood cells to become stiff, ...
In the Phase IIIB APPULSE-PNH study, adult patients with paroxysmal nocturnal hemoglobinuria (PNH) who switched to Fabhalta experienced clinically meaningful improvements in hemoglobin (Hb) levels of ...
A near-monodisperse monohydroxy-terminated polydimethylsiloxane (PDMS; mean degree of polymerization = 66) was esterified using a carboxylic acid-functionalized trithiocarbonate to yield a PDMS66 ...