Haploid embryonic stem cells (haESCs) have been established in many species. Differentiated haploid cell line types in mammals are lacking due to spontaneous diploidization during differentiation ...

Stem cell research holds huge potential for medicine and human health. In particular, human embryonic stem cells (ESCs), with their ability to turn into any cell in the human body, are essential ...

WIKIMEDIA, EKEM, MIKAEL HAGGSTROM A team of researchers from Israel and the U.S. has developed the first lines of human, haploid embryonic stems cells, according to a study published yesterday (March ...

Recent studies have reported innovative chemical strategies aimed at preserving the haploid state in embryonic stem cells by modulating key cell cycle phases and signalling pathways [5].

The researchers showed that these haploid stem cells were pluripotent ... Derivation and differentiation of haploid human embryonic stem cells. Nature, 2016; DOI: 10.1038/nature17408; ...

Nature Methods - Rat haploid embryonic stem cells. The study of gene function in diploid organisms such as the rat is impeded by the fact that each gene exists as two copies.

Researchers in the UK have received approval to conduct the first ever human trials for a stem cell treatment to reverse ...

Newstem Ltd. filed a presubmission to the U.S. FDA for a de novo request and an in vitro diagnostic device with the EMA for its Newstem software diagnostic device (NSDD). The bioinformatics-based ...

A haploid cell with 23 chromosomes (left), and a diploid cell with 46 chromosomes (right) ... Embryonic stem cells are diploid cells from which all tissues in the body are built.

The isolation of embryonic stem cells in 1998 was a fundamental breakthrough for biology. But despite high hopes new medical treatments based on those stem cells haven't materialized.

Pluripotent stem cells (PSCs) have been invaluable tools in this field, as they can transform into various cell types in the body and play key roles during early embryonic development.

More information: Gülce Perçin et al, Embryonic macrophages orchestrate niche cell homeostasis for the establishment of the definitive hematopoietic stem cell pool, Nature Communications (2025 ...