Molecular conformation is any spatial arrangement of the atoms in a molecule which can be interconverted by rotations about formally single bonds. Biopolymers, such as polynucleotides ...

Ascletis Pharma has reported positive topline outcomes from its US Phase Ia single ascending dose (SAD) study of the oral tablet, ASC30, in obese individuals. The study, which involved 40 obese ...

Glucagon prescriptions for severe hypoglycemia in Medicaid initially decreased from 2012 to 2018 but increased between 2019 and 2023 following the introduction of newer products. Glucagon ...

Rafael Rodríguez believes that "this molecule could become a drug to treat the symptoms of dementia, at least during the initial stages of the disease, because we have already seen that the body ...

Catalent’s acquisition by Novo Holdings, to help Novo Nordisk meet manufacturing demand for glucagon-like peptide (GLP)-1 obesity medicines, has taken sterile fill-finish capacity out of the market, ...

The start-up expects to advance its lead asset—a once-weekly oral glucagon-like peptide 1 (GLP-1) receptor agonist—into Phase 2 trials for weight loss and the treatment of obesity later this year.

A new study by Weill Cornell Medicine and the Boyce Thompson Institute reveals that the body produces a molecule, BA-MCY, which counteracts gut microbes’ signals to regulate bile acid production, ...

Significantly, the company is poised to make a foray into the metabolic space with its oral glucagon-like peptide-1 receptor agonist (GLP-1RA) danuglipron. In a space that is currently dominated by ...