In the first half of 2025, Ozempic developer Novo Nordisk in Bagsværd, Denmark, expects results from a second phase III trial ...

In this regard, chemical inducers of proximity (CIPs) offer a promising approach to precisely manipulate protein–protein interactions in live cells and in vivo. In this study, we introduce pMandi, a ...

Semaglutide mimics the action of the natural protein glucagon-like peptide 1(GLP-1), a hormone from a family of chemical messengers called the ... meaning its molecules mimic the structure of GLP-1, ...

Lipidated analogues of glucagon-like peptide 1 (GLP-1 ... This work provides a systematic study of the solubility, structure, oligomerization, and long-term stability of five different lipidated ...

Researchers have profiled the molecular structure and features of a key part of the deadly Nipah virus. Experiments in cells showe how changes in the viral polymerase -- a protein involved in ...

"Obesity is gradually eroding human health," and the global prevalence of obesity (BMI > 30) is predicted to reach 25 % by 2035, affecting nearly 1.9 billion people. The demand for medications to ...

Once in the pancreas, those immune cells release cytokines-tiny chemical messengers-that instruct pancreatic cells to produce the hormone glucagon. The increase in glucagon then signals the liver ...

This particular hormone has been reported in previous studies but its exact structure and importance are unclear. Since the scientists were able to produce enough of a sample from the cultures ...

Traditionally, blood sugar regulation has been attributed to the hormones insulin and glucagon, both produced ... the gut connected to the brain release chemical signals that bind to immune ...

What Is Hormone Replacement Therapy (HRT)? HRT is a possible treatment for menopause symptoms. Your doctor may also refer to the treatment as hormone therapy, menopausal hormone therapy ...