Plant scientists have used a standard "gene gun" since 1988 to genetically modify crops for better yield, nutrition, pest resistance and other valuable traits.

Many methods exist for inserting DNA into a cell, ... researchers often use so-called "gene guns" to fire particles coated with strands of DNA known as plasmids at large populations of cells.

Although geneticists use a variety of gene transfer methods to introduce foreign DNA into microbial, plant, and animal cells, many important organisms do not respond to these established techniques.

Photo: Martin Timmermann It's genetic engineering meets Guns & Ammo. In the early '80s, Cornell horticulturalist John Sanford went hunting for an efficient method of inserting new DNA into plant ...

We developed a gene gun method for the transfer of human agouti signalling protein (ASP) cDNA to alter rat skin colour in vivo. Human ASP cDNA was cloned into a modified cytomegalovirus plasmid ...

In this study, we developed a gene-gun method for the transfer of POMC cDNA in vivo, and investigated its therapeutic effect on inflammatory pain in a rat model of formalin-induced pain.

“These findings pinpoint critical limitations in the gene gun design and led us to hypothesize that engineering the flow dynamics within the gene gun could significantly improve its efficiency and ...