Announcing a new article publication for Cardiovascular Innovations and Applications journal. Alternative splicing (AS), a critical process for gene expression regulation, allows a single precursor ...

In most of the cases the breakpoint occurs in the third intron of the HMGA2 ... separates the third from the fourth exon. The HMGA proteins can also influence gene transcription through direct ...

Pathogenic variants have been identified both in the coding and non-coding regions of the gene inclusively in the 5′UTR and the 3′UTR regions. Consequently, it is important to screen all coding exons, ...

Similar motifs and similar intron/exon structures among the genes revealed that these genes may have the same functions. Figure 5. (A) Molecular functions, biological processes, and cellular component ...

The annotations can be filtered by their NDR score (see example below), read count and gene read proportion between the discovery ... If multiple transcripts share exon-junctions, only one will be ...

Boehringer will leverage ExpressionEdits' Genetic Syntax Engine which generates optimized introns to increase protein expression.

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...