PE Hub has rounded up six deals going back to early January involving companies in the oncology segment, starting with the ...

Gastrointestinal stromal tumors are among the first solid tumors for which cancer-(cell-)specific therapy became available. What is its pathogenesis, therapy strategies and drug resistance mechanisms?

Total 497 GIST patients were involved in present study, with a median age of 60 years (range 23–90) and 55.9% was male. Stomach and small bowel were the most common sites of primary disease (59. ...

In contrast, gastrointestinal stromal tumors (GISTs) represent a more common subset of mesenchymal neoplasms within the gastrointestinal tract and frequently exhibit CD117 and DOG1 positivity, ...

SU11248, a multi-targeted tyrosine kinase inhibitor, can overcome imatinib (IM) resistance caused by diverse genomic mechanisms in patients (pts) with metastatic gastrointestinal stromal tumor (GIST) ...

FDA approved to help select patients with metastatic prostate cancer for radioligand therapy before chemotherapy.

JNJ-1900 (NBTXR3) is a novel intratumoral radioenhancer, activated by radiation therapy, which is being investigated in phase 1 clinical research for patients with lung cancer, according to Dr. Jared ...

WebMD explains the use of radiation therapy for prostate cancer, including internal and external radiation therapy, how radiation therapy is performed, side effects, risks, and more.

Brain tumors are abnormal cell growths needing prompt attention. Symptoms like pe. Sign In. TOI. ... MRI and CT scans aid diagnosis. Treatment includes surgery, radiation, and chemotherapy.

With the tumor-agnostic FDA approvals of pembrolizumab in dMMR and TMB-H solid tumors (≥ 10 mutations per Mb DNA) and of larotrectinib and entrektinib in NTRK fusion–positive solid tumors, multigene ...

Drug resistance in solid tumors remains a major obstacle in oncology, frequently leading to treatment failure and disease relapse. A central contributor to ...

251776 Introduction: Recently, there are some studies showing the value of 68Ga-DOTA-FAPI-04 PET in the detection of metastatic gastrointestinal stromal tumor (GIST). However, only a few cases have ...